SODIUM BICARBONATE 8.4% injectable

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    Last updated: October 2024

     

    Prescription under medical supervision

     

    Indications

    • Severe metabolic acidosis

    Forms and strengths

    • 10 ml ampoule

    Composition

    • Sodium bicarbonate: 8.4 g per 100 ml
      • Hypertonic solution
      • Ionic composition:
        • sodium (Na+): 10 mmol (10 mEq) per 10 ml ampoule
        • bicarbonate: 10 mmol (10 mEq) per 10 ml ampoule

    Contra-indications, adverse effects, precautions

    • Do not use in case of alkalosis or respiratory acidosis.
    • Do not administer hypertonic solutions by IM or SC route. Administer under close medical supervision, by slow direct IV injection diluted in 5% glucose or by continuous infusion in 5% glucose.
    • Do not add: penicillins, chloramphenicol, aspirin, atropine, calcium, insulin, vitamins, etc. to sodium bicarbonate solution.

    Remarks

    • Contains a high concentration of bicarbonate and sodium ions. Its use is rarely justified in case of metabolic acidosis caused by dehydration. Inaccurate administration may induce hypernatraemia and hypokalaemia.

    Storage

    Below 25 °C

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