FUROSEMIDE injectable

Prescription under medical supervision


Therapeutic action

– Diuretic

Indications

– Emergency treatment of:
• Oedema caused by renal, hepatic or congestive heart failure
• Hypertensive crisis (except that of pregnancy)
• Pulmonary oedema

Forms and strengths, route of administration

– 20 mg in 2 ml ampoule (10 mg/ml) for IM or slow IV injection

Dosage

– Child: 0.5 to 1 mg/kg/injection
– Adult: 20 to 40 mg/injection
Repeat after 2 hours if necessary.

– For pulmonary oedema: if an initial IV injection of 40 mg does not produce a satisfactory response within one hour, the dose may be increased to 80 mg by slow IV injection.

Duration

– According to clinical response;
– If prolonged use is required, change to oral treatment 3 hours after the last injection.

Contra-indications, adverse effects, precautions

– Do not administer in other types of oedema, especially those due to kwashiorkor.
– Do not administer in case of hepatic encephalopathy.
– May cause: hypokalaemia, especially in cases of cirrhosis, denutrition, congestive heart failure.
– Closely monitor combination with digoxin (furosemide enhances toxicity of digoxin).
– PregnancyCONTRA-INDICATED to treat hypertension in pregnancy
– Breast-feeding: avoid (excreted in milk and may reduce milk production)

Remarks

– If doses greater than 50 mg are required, it is recommended that they be given by IV infusion.
– Storage: below 25 °C -