SODIUM BICARBONATE 8.4% injectable

Prescription under medical supervision


– Severe metabolic acidosis

Forms and strengths

– 10 ml or 20 ml ampoule


Sodium bicarbonate: 8.4 g per 100 ml
– Hypertonic solution
– Ionic composition:

sodium (Na+): 10 mmol (10 mEq) per 10 ml ampoule
bicarbonate: 10 mmol (10 mEq) per 10 ml ampoule

Contra-indications, adverse effects, precautions

– Do not use in case of alkalosis or respiratory acidosis.
– Do not administer hypertonic solutions by IM or SC route. Administer under close medical supervision, by slow direct IV injection diluted in 5% glucose or by continuous infusion in 5% glucose.
– Do not add: penicillins, chloramphenicol, aspirin, atropine, calcium, insulin, vitamins, etc. to sodium bicarbonate solution.


– Contains a high concentration of bicarbonate and sodium ions. Its use is rarely justified in case of metabolic acidosis caused by dehydration. Inaccurate administration may induce hypernatraemia and hypokalaemia.
– Storage: below 25 °C